Close-up of a white medicine bottle with a black cap, labeled Tesamorelin from Guardian Labs, against a pale blue background.
Label
-20% Off

Tesamorelin

Original price was: $70.00.Current price is: $56.00.

Earn 56 points with Guardian Rewards

20% off storewide — 20% off ends in 17hrs35min53sec

Product Left: 50

Stack More. Save More.
  • 3+ vials: 5% off
  • 5+ vials: 10% off
  • 10+ vials: 15% off
Discounts apply automatically in your cart. Mix and match eligible vials to qualify.

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.gl-short-meta span { color: #4a90d9 !important; margin-right: 0.8rem !important; }
.gl-short-meta span::before { content: “25CF” !important; margin-right: 0.3rem !important; }

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}
.gl-short-tagline em { font-style: italic !important; color: #4a90d9 !important; }

/* Key benefits list */
.gl-short-benefits {
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}
.gl-short-benefits li {
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border-bottom: 1px solid #eef2f7 !important;
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.gl-short-benefits li::before {
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}
.gl-short-benefits li strong { color: #0a2540 !important; font-weight: 600 !important; }

/* Spec strip */
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/* Research use badge */
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font-family: -apple-system, BlinkMacSystemFont, sans-serif !important;
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text-transform: uppercase !important;
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}

/* ============ RESPONSIVE — MOBILE ============ */
@media (max-width: 768px) {
.gl-short-meta { font-size: 0.6rem !important; line-height: 1.7 !important; }
.gl-short-meta span { display: inline-block !important; margin-right: 0.7rem !important; }
.gl-short-tagline {
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padding-left: 0.8rem !important;
border-left-width: 3px !important;
}
.gl-short-benefits li {
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padding: 0.5rem 0 0.5rem 1.4rem !important;
line-height: 1.5 !important;
}
.gl-short-specs {
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}
.gl-short-specs td {
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}
.gl-short-specs strong { font-size: 0.95rem !important; }
.gl-short-specs em { font-size: 0.55rem !important; letter-spacing: 0.08em !important; }
.gl-short-badge { font-size: 0.58rem !important; padding: 0.3rem 0.6rem !important; }
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@media (max-width: 380px) {
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.gl-short-benefits li { font-size: 0.85rem !important; }
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}

GHRH AnalogueResearch Peptide
A synthetic 44-amino-acid analogue of growth hormone releasing hormone — modified at the N-terminus with a trans-3-hexenoyl group for enhanced stability.
  • Selective action on visceral adipose tissue (VAT)
  • Pulsatile GH release via pituitary GHRH receptor agonism
  • Extended half-life vs. native GHRH
  • Studied for metabolic, cognitive, and muscle-density applications
> 99%HPLC Purity 5 / 10 mgVial Sizes −20°CStorage

Research Use Only

50 in stock

Delivery Frequency:
Add to wishlist

SKU: GL-TESA-10 Categories: , Brand:

Third-Party Testing

Tested lot
GLTESA10-V01-2608-01
Laboratory
Kovera Labs
Purity
99.803%
Test date
08/10/2026 (Certified)

View full testing record →  |  Original COA (PDF)

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    Description

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    /* No dark background. Navy left border + navy text. */
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    /* ============ QUICK FACTS BAND ============ */
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    /* ============ SECTIONS ============ */
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    /* ============ MECHANISM — light cards ============ */
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    /* ============ APPLICATIONS ============ */
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    font-family: “SF Mono”, Menlo, Consolas, monospace !important;
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    /* ============ STUDIES ============ */
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    /* ============ RESPONSIVE — TABLET ============ */
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    display: block !important;
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    /* ============ RESPONSIVE — MOBILE ============ */
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    font-size: 1.55rem !important;
    line-height: 1.2 !important;
    margin-bottom: 0.8rem !important;
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    Research PeptideGHRH AnalogueLot Verified

    Tesamorelin
    trans-3-hexenoyl GHRH

    A synthetic 44-amino-acid analogue of growth hormone releasing hormone — modified at the N-terminus for enhanced stability and studied for its selective action on visceral adiposity.

    > 99% PurityHPLC VerifiedLyophilized Powder5mg & 10mg Vials

    > 99%HPLC Purity
    5135.73MW (Da)
    44 AAPeptide Length
    −20°CStorage

    § 01 — The Compound

    A longer-acting analogue of native GHRH, engineered for specificity.

    Tesamorelin is widely recognized in the scientific community for its unique ability to stimulate the release of growth hormone with a high degree of specificity. Unlike other GHRH analogues, it has been the subject of extensive clinical research specifically regarding the reduction of visceral adipose tissue.

    At Guardian Labs, we provide research-grade Tesamorelin rigorously tested to ensure purity exceeding ninety-nine percent — ensuring your laboratory data regarding visceral adiposity and pituitary function remains accurate and reproducible.
    The addition of the trans-3-hexenoyl group allows the peptide to remain active in the system longer than natural GHRH — providing sustained, pulsatile stimulation of the pituitary.

    § 02 — Mechanism of Action

    A cascade, not a switch — from receptor to response.

    i

    Receptor Binding

    Tesamorelin acts as a potent agonist of the GHRH receptor on somatotroph cells of the anterior pituitary.

    		 ii

    GH Synthesis

    Upon binding, the pituitary initiates synthesis and secretion of endogenous growth hormone in a pulsatile pattern.

    		 iii

    Hepatic Signalling

    Circulating growth hormone triggers the liver to produce IGF-1, the principal downstream mediator.

    		 iv

    Lipolytic Action

    The pulsatile pattern promotes lipolysis preferentially within visceral fat depots.

    ✦

    On Specificity

    Research distinguishes Tesamorelin from peptides such as CJC-1295 due to its documented preference for visceral — rather than subcutaneous — adipose reduction, a finding that has shaped its entire investigative focus.

    § 03 — Research Applications

    Primary subjects of investigation — strictly laboratory use.

    A.01

    Visceral Adiposity

    Investigating the reduction of deep abdominal fat in metabolic syndrome models, with attention to selectivity against subcutaneous depots.

    		 A.02

    Cognitive Function

    Research into the effects of GHRH analogues on executive function, verbal memory, and models of mild cognitive impairment.

    		 A.03

    Muscle Quality

    Studies analyzing the relationship between reduced myosteatosis — fat infiltration within muscle — and improved muscle density.

    § 04 — Scientific References

    Peer-reviewed literature supporting the research potential of this peptide.

    i.

    Reduction of Visceral Adipose Tissue

    In a landmark randomized clinical trial involving subjects with abdominal fat accumulation, Tesamorelin administration resulted in a significant reduction in visceral adipose tissue area — without altering subcutaneous fat or body mass index significantly.
    ii.

    Cognitive Function & MCI

    This study examined the effects of GHRH administration on cognitive function in healthy older adults and those with mild cognitive impairment. Results indicated a favorable effect on executive function and verbal memory.
    iii.

    Improvement in Muscle Density

    A secondary analysis of clinical trials found that Tesamorelin treatment was associated with significant increases in paraspinal muscle density — suggesting reduced fat infiltration within muscle tissue.

    § 05 — Product Specifications

    Certificate of analysis available upon request.

    Sequence trans-3-hexenoyl-[Tyr¹]hGRF(1-44)NH₂ Format Lyophilized Powder (Freeze-dried) Vial Size 5 mg / 10 mg Purity > 99% (HPLC Verified) Storage Store at −20°C Reconstitution Bacteriostatic Water

    Research Use OnlyAll products listed are intended exclusively for laboratory research and development purposes. They are not intended for human consumption, diagnostic, or therapeutic use. Customers must be at least 18 years of age to purchase.

    Additional information

    Weight 0.0625 lbs
    Vial Size

    5MG, 10MG

    Independent Laboratory Testing

    View available Certificates of Analysis for this research product.

    Previous batches

    Lot GL-TES10MG-02-202608-001 Lot page
    Browse all Certificates of Analysis

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