Description

Wolverine Blend (BPC-157 / TB-500)

The Wolverine Blend is a premier research formulation combining two of the most regenerative peptides in modern science: BPC-157 (Body Protection Compound) and TB-500 (Thymosin Beta-4 Fragment). This 1:1 synergistic blend is designed to investigate accelerated recovery pathways by targeting two distinct biological mechanisms simultaneously.

At Guardian Labs, we offer this pre-mixed formulation to provide researchers with a convenient, high-purity solution for studying soft tissue repair and cellular migration. Every vial is HPLC-verified to contain >99% purity.

What is the Wolverine Blend?

The “Wolverine” nickname stems from the research community’s observation of this blend’s potential for rapid tissue recovery. It combines:

1. BPC-157: A pentadecapeptide derived from human gastric juice, known for its ability to upregulate Growth Hormone Receptors and promote angiogenesis (new blood vessel formation).

2. TB-500: A synthetic fraction of the protein thymosin beta-4, which is critical for actin regulation and cell motility (the movement of cells to the site of injury).

By combining these two, researchers can observe a multi-faceted approach to healing: BPC-157 improves the vascular supply to the area, while TB-500 aids the structural organization of the cells.

Mechanism of Action

The Wolverine Blend operates via a dual-action pathway:

• Angiogenesis (BPC-157): Research indicates that BPC-157 stimulates the expression of the VEGF (Vascular Endothelial Growth Factor) pathway. This increases blood flow and nutrient delivery to damaged tissues, such as tendons and ligaments.

• Actin Sequestration (TB-500): TB-500 binds to actin, a protein essential for cell structure. By regulating actin polymerization, it facilitates the migration of keratinocytes and endothelial cells to the injury site, effectively “closing the gap” in damaged tissue.

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  Potential Research Applications

This blend is frequently utilized in studies focusing on high-impact recovery and structural integrity. Key areas of interest include:

• Connective Tissue Repair: Evaluating the healing rate of tendons, ligaments, and skeletal muscle in animal models.

• Inflammation Modulation: Investigating how the combination reduces inflammatory markers in acute injury phases.

• Cytoprotection: Studies suggesting BPC-157 offers systemic protection to the gut lining and organ tissues against toxin-induced damage.

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  Scientific References

To validate the synergistic potential of these peptides, we reference the following peer-reviewed studies regarding their individual efficacy in tissue repair.

1. BPC-157 and Tendon Healing

Summary: In this study, BPC-157 was administered to rats with transected Achilles tendons. The results showed significantly accelerated healing, with improved load-to-failure strength and better collagen organization compared to controls, suggesting potent soft-tissue repair properties.

• View the study on PubMed

2. Thymosin Beta-4 (TB-500) and Muscle Regeneration

Summary: This research focused on the role of Thymosin Beta-4 in skeletal muscle. The findings demonstrated that the peptide promotes cell migration and survival, accelerating the regeneration of muscle fibers after injury and reducing scar tissue formation.

• View the study on PubMed

3. Angiogenic Effects of BPC-157

Summary: This trial explored the mechanism behind BPC-157’s healing capabilities. Researchers identified that the peptide stimulates the nitric oxide system, leading to enhanced protection of endothelial cells and rapid formation of new blood vessels (angiogenesis).

• View the study on PubMed

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  Product Specifications

• Components: BPC-157 (Pentadecapeptide) & TB-500 (Thymosin Beta-4 Frag)

• Format: Lyophilized Powder (Freeze-dried)

• Ratio: 1:1 Blend (e.g., 5mg BPC / 5mg TB-500)

• Purity: >99% (HPLC Verified)

• Storage: Store at -20°C. Reconstitute with Bacteriostatic Water.

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  Disclaimer: All products listed on this site are for laboratory research and development purposes only. They are not intended for human consumption, diagnostic, or therapeutic use. Customers must be at least 18 years old to purchase.