Description
ARA-290
ARA-290 peptide (cibinetide) is an 11-amino-acid fragment modeled on the helix-B surface of erythropoietin, studied for Innate Repair Receptor signaling without erythropoietic activity. HPLC-verified above 99% purity, with a lot COA in our library.
What is ARA-290?
ARA-290, also known as cibinetide, is a synthetic 11-amino-acid peptide that reproduces the three-dimensional helix-B surface of erythropoietin (EPO). It was designed to keep EPO’s tissue-protective signaling while removing its effect on red blood cell production. Guardian Labs supplies ARA-290 as a lyophilized research peptide, HPLC-verified above 99% purity.
Mechanism studied in research
i
Innate Repair Receptor (IRR)Binds the EPOR/CD131 heterocomplex rather than the classical EPOR homodimer |
ii
Context-restricted signalingThe IRR is expressed locally on stressed or injured tissue in research models |
iii
Inflammatory signalingStudied for effects on pro-inflammatory cytokine pathways in preclinical work |
Specifications
| Also known as | Cibinetide, helix-B surface peptide |
| Sequence length | 11 amino acids |
| Molecular weight | 1257.3 Da |
| Purity | >99% (HPLC) |
| Vial sizes | 10mg, 16mg |
| Form · storage | Lyophilized powder · −20°C |
Quality and testing
The current 10mg lot’s Certificate of Analysis is in our COA library.
Frequently asked questions
Is ARA-290 the same as EPO?
No. It’s a short fragment modeled on one surface of EPO and is studied specifically because it lacks EPO’s erythropoietic activity.
How should ARA-290 be stored?
As a lyophilized powder at −20°C, protected from light.
What sizes are available?
10mg and 16mg vials.
Research Use OnlyFor laboratory research use only. Not for human consumption. Must be 21+ to purchase. Not intended to diagnose, treat, cure or prevent any disease.
Reviews
There are no reviews yet.