Description
Cagrilintide 5mg
Cagrilintide 5mg is a long-acting, acylated analog of the pancreatic hormone amylin, studied in satiety-signaling and energy-balance research. HPLC-verified at 99.81% purity, with a lot COA in our library.
What is Cagrilintide?
Cagrilintide is a synthetic 37-amino-acid analog of amylin, a peptide hormone co-released with insulin from pancreatic beta cells. It carries a fatty-acid side chain that binds albumin, which gives it a much longer half-life in research models than native amylin. Guardian Labs supplies Cagrilintide 5mg as a lyophilized research peptide, HPLC-verified at 99.81% purity and lot-verified so every vial is consistent from one experiment to the next.
Mechanisms studied in Cagrilintide research
i
Amylin and calcitonin receptorsActivates both receptor families, often described as a dual amylin-calcitonin receptor agonist |
ii
Satiety signalingHindbrain and hypothalamic appetite pathways in animal models |
iii
Gastric emptyingRate of gastric emptying and post-meal glucagon response |
iv
Combination researchStudied alongside GLP-1 receptor agonists in energy-balance research |
Specifications
| Compound class | Long-acting acylated amylin analog |
| Length | 37 amino acids |
| Molecular weight | ~4,409 Da |
| Purity | 99.81% (HPLC) |
| Amount · storage | 5mg per vial, lyophilized · −20°C |
Quality and testing
The current lot’s Certificate of Analysis is in our COA library.
Frequently asked questions
What is amylin?
A 37-amino-acid peptide hormone released by the pancreas together with insulin. Cagrilintide is a modified, longer-acting analog of it.
Why is it called long-acting?
Its attached fatty-acid chain binds albumin in circulation, which slows its clearance compared with native amylin in research models.
How is it reconstituted?
With bacteriostatic water, then stored at 4°C.
Research Use OnlyFor laboratory research use only. Not for human consumption. Must be 21+ to purchase. Not intended to diagnose, treat, cure or prevent any disease.
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