Description
BPC-157
Body Protection Compound
A stable 15-amino-acid pentadecapeptide derived from a protective protein found in human gastric juice — extensively studied for its systemic regenerative and cytoprotective properties.
A pentadecapeptide fragment of a naturally occurring protective protein.
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BPC-157 is a synthetic pentadecapeptide corresponding to a partial sequence of Body Protection Compound, a larger protective polypeptide originally isolated from human gastric juice. Unlike many peptides, it remains remarkably stable across a wide pH range — a property that has made it a subject of extensive investigation in models of systemic injury and recovery. At Guardian Labs, we provide research-grade BPC-157 rigorously tested to ensure purity exceeding ninety-nine percent — ensuring your laboratory data regarding tissue repair and cytoprotection remains accurate and reproducible. |
BPC-157 is notable for its apparent activity across multiple organ systems — from gastrointestinal mucosa to tendon, vasculature, and central nervous tissue — suggesting a systemic, rather than tissue-specific, mechanism.
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A convergence of pathways — from vascular formation to neurotransmitter modulation.
i
Angiogenic SignallingUpregulates VEGF receptor 2 expression, promoting the formation of new vasculature essential for tissue repair and recovery. |
ii
Nitric Oxide PathwayModulates the NO system, influencing vascular tone, blood flow, and mucosal integrity in models of injury. |
iii
Growth Factor ActivityInteracts with pathways governing fibroblast migration, collagen synthesis, and the formation of granulation tissue. |
iv
Gut-Brain AxisInfluences dopaminergic and serotonergic systems — a proposed link between gastric origin and central nervous activity. |
On Stability
BPC-157 distinguishes itself from most peptides through its resistance to gastric acid hydrolysis and its stability across a wide pH range — a property that has supported its broad use in oral and systemic administration studies across decades of research.
Primary subjects of investigation — strictly laboratory use.
A.01Tissue RepairAccelerated healing in soft tissue and musculoskeletal injury models, including muscle strain and soft-tissue disruption. |
A.02Gut & GI TractInvestigations into gastric and intestinal mucosal protection, models of inflammatory bowel injury, and epithelial healing. |
A.03Tendon & LigamentStudies of tendon-to-bone healing, ligament repair, fibroblast migration, and collagen matrix remodeling. |
A.04AngiogenesisResearch into new blood vessel formation, VEGF pathway activation, and restoration of perfusion in ischemic tissue models. |
A.05NeuroprotectionModels examining neuronal recovery, CNS injury, and the modulation of dopaminergic activity via the gut-brain axis. |
Peer-reviewed literature supporting the research potential of this peptide.
| i. |
Tendon & Musculoskeletal HealingA seminal investigation into BPC-157 administration in a transected Achilles tendon model reported accelerated tenocyte migration, enhanced cellular outgrowth, and improved functional recovery — establishing the peptide as a focus of ongoing musculoskeletal repair research. |
View on PubMed → |
| ii. |
Gastrointestinal CytoprotectionA body of research spanning multiple ulcer and colitis models found that BPC-157 administration was associated with accelerated mucosal healing, preserved epithelial integrity, and reduced lesion severity — consistent with its original characterization as a protective gastric peptide. |
View on PubMed → |
| iii. |
Angiogenesis & VEGF SignallingInvestigators reported that BPC-157 upregulated VEGF receptor 2 expression and promoted new blood vessel formation in injured tissue — a mechanistic finding that helps explain the peptide’s broad activity across organ systems. |
View on PubMed → |
| iv. |
Central Nervous System EffectsStudies in rodent models have reported that BPC-157 exerts neuroprotective effects and influences dopaminergic neurotransmission — supporting the hypothesis of a functional link between gastric-origin peptides and central nervous activity via the gut-brain axis. |
View on PubMed → |
Certificate of analysis available upon request.
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| Molecular Formula | C₆₂H₀₀N₁₆O₁₆ |
| Molecular Weight | 1419.55 g/mol |
| CAS Number | 137525-51-0 |
| Format | Lyophilized Powder (Freeze-dried) |
| Vial Size | 10 mg |
| Purity | > 99% (HPLC Verified) |
| Storage | Store at −20°C |
| Reconstitution | Bacteriostatic Water |
All products listed are intended exclusively for laboratory research and development purposes. They are not intended for human consumption, diagnostic, or therapeutic use. Customers must be at least 18 years of age to purchase.
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